In this essay I argue that there is an extended and complex meditation on the status of humanity that is at the center of the Star Trek enterprise, one that can contribute to our current interest in human-technology relations and the posthuman. Paying particular attention to the manner in which Star Trek negotiates the human-machine boundary and drawing on the work of feminist theorists such as Annette Baier, Nancy Chodorow, Carol Gilligan, and Nancy Hartsock, I argue that implicit in the show’s dealings with marginal, technological beings is an understanding of the nature of second personhood which suggests that human beings are interdependent, ineluctably social, relational, and embodied beings.